GITR/TNFRSF18 Protein, Mouse, Recombinant (aa 22-153, His)

Ref. TM-TMPK-01086

Produktinformation

• Name: GITR/TNFRSF18 Protein, Mouse, Recombinant (aa 22-153, His)
• Synonyme: TNFRSF18, AITR, GITR-D, CD357, GITR

Beschreibung

GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. GITR/TNFRSF18 Protein, Mouse, Recombinant (aa 22-153, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q8C4K3.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 15.2 kDa (predicted). Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
• Farbe/Form: Solid