FOLR4/Juno Protein, Mouse, Recombinant (His)

Ref. TM-TMPK-01171

Produktinformation

• Name: FOLR4/Juno Protein, Mouse, Recombinant (His)
• Synonyme: Juno, FOLR4, LOC390243, Folate receptor 4, FR δ, FR-delta, Folbp3, Izumo1r, FR delta, FR-δ

Beschreibung

Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno; formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Juno are both healthy but sterile. Here, both sperm-egg binding proteins are shown to be evolving under positive selection. Juno's presence in mammals alone, suggesting a recent mammalian-specific duplication and neofunctionalization of the ancestral folate receptor. FOLR4/Juno Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 24.7 kDa and the accession number is Q9EQF4-1.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 24.7 kDa (predicted). Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result.
• Farbe/Form: Solid