TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)

Ref. TM-TMPY-02271

Produktinformation

• Name: TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)
• Synonyme: thioredoxin reductase 1, TR1, TXNR, TR, TRXR1, GRIM-12

Beschreibung

Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor the development of Drug-induced liver injury (DILI), which is the most common adverse drug reaction.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 55 kDa (predicted)
• Farbe/Form: Solid