Eotaxin-2 Protein, Human, Recombinant (His)

Ref. TM-TMPY-02795

Produktinformation

• Name: Eotaxin-2 Protein, Human, Recombinant (His)
• Synonyme: MPIF-2, chemokine (C-C motif) ligand 24, SCYA24, MPIF2, Ckb-6

Beschreibung

CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL24 displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. CCL24 is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. CCL24 is chemotactic for resting T-lymphocytes, and eosinophils. It has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. It is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Eotaxin-2 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils. Elevated level of Eotaxin-2 has been seen in patients with aspirin-exacerbated respiratory disease.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 11.8 kDa (predicted)
• Farbe/Form: Solid