BBOX1 Protein, Human, Recombinant (His & GST)

Ref. TM-TMPY-03756

Produktinformation

• Name: BBOX1 Protein, Human, Recombinant (His & GST)
• Synonyme: butyrobetaine (γ), 2-oxoglutarate dioxygenase (γ-butyrobetaine hydroxylase) 1, BBOX, butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1, butyroβine (gamma), 2-oxoglutarate dioxygenase (gamma-butyroβine hydroxylase) 1, γ-BBH, gamma-BBH, BBH, G-BBH

Beschreibung

BBOX1, also known as gamma-BBH, belongs to thegamma-BBH/TMLD family. It is highly expressed in kidney and moderately expressed in liver. BBOX1 catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation. BBOX1 is an inhibition target for mildronate which can be used to treatanginaandmyocardial infarction. Mildronate may also be beneficial for the treatment ofneurological disorder,diabetes, andseizures andalcohol intoxication.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 72.5 kDa (predicted)
• Farbe/Form: Solid