FRZB Protein, Human, Recombinant (His)

Ref. TM-TMPY-03847

Produktinformation

• Name: FRZB Protein, Human, Recombinant (His)
• Synonyme: frizzled-related protein, FRITZ, OS1, SFRP3, FRZB-PEN, FRP-3, FRE, FZRB, FRZB1, FRZB-1, SRFP3, hFIZ

Beschreibung

FRZB also known as sFRP-3, is a secreted protein containing a domain similar to the putative Wnt-binding region of the frizzled family of transmembrane receptors. FRZB is widely expressed in adult mammalian tissues. In the Xenopus gastrula, FRZB is regulated as a typical Spemann organizer component. FRZB also functions as a competitor for the cell-surface G-protein receptor Frizzled. It is espically important in embryonic development. Defects in FRZB gene can cause female-specific osteoarthritis (OA) susceptibility. FRZB may serve an important role in determining hip shape and may modify the relationship between hip shape and OA.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 34.5 kDa (predicted)
• Farbe/Form: Solid