4,5-Dimethoxycanthin-6-one

CAS: 18110-87-7

Ref. TM-TN3013

Produktinformation

• Name: 4,5-Dimethoxycanthin-6-one
• Synonyme: Methylnigakinone, 4,5-Dimethoxy-β-canthin-6-one, 6H-Indolo(3,2,1-de)(1,5)naphthyridin-6-one, 4,5-dimethoxy-, O-Methylnigakinone
• CAS: 18110-87-7

Beschreibung

4,5-Dimethoxycanthin-6-one is an alkaloid isolated from Picrasma quassioides BENNET (Simaroubaceae).4,5-Dimethoxycanthin-6-one was isolated from Picrasma quassioides BENNET (Simaroubaceae) with antimicrobial activity.4,5-Dimethoxycanthin-6-one was isolated from Picrasma quassioides BENNET (Simaroubaceae) with antimicrobial activity. Dimethoxycanthin-6-one is a potent, non-competitive inhibitor of CYP1A2-mediated phenacetin O-deethylation (IC50: 1.7 μM, Ki: 2.6 μM), and a potent inhibitor of cyclic adenosine monophosphate (cAMP) phosphodiesterase.4,5-(4,5-Dimethoxycanthin-6-one) is an alkaloid isolated from Picrasma quassioides BENNET (Simaroubaceae). 4,5-Dimethoxycanthin-6-one has antimicrobial activity against Staphylococcus aureus and its drug-resistant strains.4,5-Dimethoxycanthin-6-one is cytotoxic to the tumor cell lines U937 and HepG2.4,5-Dimethoxycanthin-6-one is a cytotoxicity inhibitor (IC50 : Ki : 6 μM, Ki : 6 μM).

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 280.28
• Formel: C₁₆H₁₂N₂O₃
• Reinheit: 98.84%
• Farbe/Form: Solid