TRV-120027 TFA

Ref. TM-TP2158

Produktinformation

• Name: TRV-120027 TFA
• Synonyme: TRV-120027 TFA (1234510-46-3 free base)

Beschreibung

TRV-120027 TFA is an angiotensin II-mediated vasoconstriction inhibitor and increases cardiomyocyte contractility. TRV-120027 TFA is a β-arrestin-1-biased AT1R agonist engaging ß-arrestins while blocking G-protein signaling[1]. TRV-120027 TFA induces acute catecholamine secretion through cation channel subfamily C3 (TRPC3) coupling and promotes the formation of a macromolecular complex composed of AT1R-β-arrestin-1-TRPC3-PLCγ at the plasma membrane.

• Marke: Targetmol

Chemische Eigenschaften

• Molekulargewicht: 1040.1
• Formel: C₄₅H₆₈F₃N₁₃O₁₂
• Reinheit: 97.45%
• Farbe/Form: Solid