Abiraterone-d4

CAS: 2122245-62-7

Ref. TR-A108492

Produktinformation

• Name: Abiraterone-d4
• Synonyme: (3ß)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol-d4, CB 7598-d4
• CAS: 2122245-62-7

Beschreibung

Applications Labelled Abiraterone (A108490). A steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
References Denis, L., et al.: Cancer, 72, 3888 (1993), Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995), Denmeade, S., et al.: Nat. Rev., 2, 389(2002), Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 353.53
• Formel: C₂₄H₂₇D₄NO
• Farbe/Form: Off-White
• InChl: InChI=1S/C24H31NO/c1-23-11-9-18(26)14-17(23)5-6-19-21-8-7-20(16-4-3-13-25-15-16)24(21,2)12-10-22(19)23/h3-5,7,13,15,18-19,21-22,26H,6,8-12,14H2,1-2H3/t18-,19-,21-,22-,23-,24+/m0/s1/i3D,4D,13D,15D
• InChI Key: InChIKey=GZOSMCIZMLWJML-UQHOXKPTSA-N
• SMILES: [2H]c1nc([2H])c(C2=CC[C@H]3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)c([2H])c1[2H]