Abiraterone Acetate

CAS: 154229-18-2

Ref. TR-A108500

Produktinformation

• Name: Abiraterone Acetate
• Synonyme: CB 7630, Zytiga, (3beta)-17-(3-Pyridinyl)-androsta-5,16-dien-3-ol Acetate (Ester), (3beta)-17-(3-Pyridinyl)androsta-5,16-dien-3-yl acetate, (3)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol Acetate (Ester), (3Beta,8Xi,9Xi,14Xi)-17-(Pyridin-3-Yl)Androsta-5,16-Dien-3-Yl Acetate, (3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-yl acetate, Androsta-5,16-dien-3-ol, 17-(3-pyridinyl)-, acetate (ester), (3β)-, Cb 7630

Beschreibung

Applications Abiraterone acetate is a novel steroidal inhibitor of human Cytochrome P450 (17α-Hydroxylase-C17,20-lyase): potential agent for the treatment of prostatic cancer.
References Denis, L., et al.: Cancer, 72, 3888 (1993), Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995), Denmeade, S., et al.: Nat. Rev., 2, 389(2002), Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 391.55
• Formel: C₂₆H₃₃NO₂
• Farbe/Form: Neat
• InChl: InChI=1S/C26H33NO2/c1-17(28)29-20-10-12-25(2)19(15-20)6-7-21-23-9-8-22(18-5-4-14-27-16-18)26(23,3)13-11-24(21)25/h4-6,8,14,16,20-21,23-24H,7,9-13,15H2,1-3H3/t20-,21-,23-,24-,25-,26+/m0/s1
• InChI Key: InChIKey=UVIQSJCZCSLXRZ-UBUQANBQSA-N
• SMILES: CC(=O)O[C@H]1CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CC=C(c5cccnc5)[C@@]4(C)CC[C@@H]32)C1