Aclerastide

CAS: 227803-63-6

Ref. TR-A115630

Produktinformation

• Name: Aclerastide
• Synonyme: 3-L-Norleucine-5-L-isoleucine-1-7-angiotensin II, 1: PN: WO2013119870 SEQID: 4 claimed protein, 1: PN: WO2013158959 SEQID: 4 claimed protein 38: PN: WO0144270 SEQID: 41 claimed protein, 39: PN: WO0143761 SEQID: 41 claimed protein, 39: PN: WO0155176 SEQID: 41 claimed protein, 39: PN: WO02087504 SEQID: 41 claimed protein 40: PN: WO0198325 SEQID: 41 claimed protein, 41: PN: WO0056345 SEQID: 41 claimed sequence, 44: PN: WO0002905 SEQID: 45 claimed protein, 5: PN: WO2010028845 SEQID: 5 claimed protein 7: PN: WO0009144 SEQID: 41 claimed protein, 7: PN: WO9958140 SEQID: 41 claimed protein
• Marke: TRC
• Beschreibung: Applications Aclerastide is a peptide analog of angiotensin II, and a potential treatment for diabetic foot ulcers.References Nguyen, T. T., et al.: Eur. J. Pharmacol., 834, 77 (2018); Rodgers, K., et al.: Expert. Opin. on Investig. Drugs, 20, 1575 (2011)

Chemische Eigenschaften

• Molekulargewicht: 913.031
• Formel: C₄₂H₆₄N₁₂O₁₁
• Farbe/Form: Neat
• InChl: InChI=1S/C42H64N12O11/c1-4-6-9-28(50-36(59)29(10-7-16-47-42(44)45)49-35(58)27(43)20-33(56)57)37(60)51-30(18-24-12-14-26(55)15-13-24)38(61)53-34(23(3)5-2)39(62)52-31(19-25-21-46-22-48-25)40(63)54-17-8-11-32(54)41(64)65/h12-15,21-23,27-32,34,55H,4-11,16-20,43H2,1-3H3,(H,46,48)(H,49,58)(H,50,59)(H,51,60)(H,52,62)(H,53,61)(H,56,57)(H,64,65)(H4,44,45,47)/t23-,27-,28-,29-,30-,31-,32-,34-/m0/s1
• InChI Key: InChIKey=RUBMHAHMIJSMHA-LBWFYSSPSA-N
• SMILES: CCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O)[C@@H](C)CC