N-Acetyl Mesalazine

CAS: 51-59-2

Ref. TR-A168320

Produktinformation

• Name: N-Acetyl Mesalazine
• Synonyme: 5-Acetaminosalicylic Acid, 2-Hydroxy-5-(acetylamino)benzoic acid, 2-Hydroxy-5-acetamidobenzoic acid, 2-Hydroxy-5-acetylaminobenzoic acid, 3-Carboxyparacetamol, 5-(Acetylamino)-2-Hydroxybenzoic Acid, 5-(Acetylamino)salicylic acid, 5-Acetamido-2-hydroxybenzoic acid, Acetylmesalazine, Benzoic acid, 5-(acetylamino)-2-hydroxy-, Benzoic acid, 5-(acetylamino)-2-hydroxy- (9CI), Cj 46A, N-Acetyl-5-aminosalicylic acid, Nsc 54183, Salicylic acid, 5-acetamido-, Salicylic acid, 5-acetamido- (8CI)

Beschreibung

Stability Hygroscopic
Applications N-Acetyl Mesalazine is an metabolite of Mesalazine. A Salicylic Acid derivative. Inhibitor of recombinant human thiopurine methyltransferase (hTPMT).
References Bondesen, S., et al.: Br. J. Clin. Pharmacol., 25, 269 (1988), Brogden, R., et al.: Drugs, 38, 500 (1989), Jensen, J., et al.: Biochem. Pharmacol., 45, 1201 (1993), Liu, Z., et al.: Drug Metab. Dispos., 23, 246 (1995), Vree, T., et al.: Clin. Drug Invest., 20, 35 (2000),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 195.17
• Formel: C₉H₉NO₄
• Farbe/Form: Neat
• InChl: InChI=1S/C9H9NO4/c1-5(11)10-6-2-3-8(12)7(4-6)9(13)14/h2-4,12H,1H3,(H,10,11)(H,13,14)
• InChI Key: InChIKey=GEFDRROBUCULOD-UHFFFAOYSA-N
• SMILES: CC(=O)Nc1ccc(O)c(C(=O)O)c1