(±)-N-[3-Acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]propanamide Monohydrochloride

CAS: 57898-79-0

Ref. TR-A178980

Produktinformation

• Name: (±)-N-[3-Acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]propanamide Monohydrochloride
• Synonyme: Acebutolol Imp. J (EP),N-[3-Acetyl-4-[(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]propanamide Hydrochloride, Acebutolol Hydrochloride Imp. J (EP) as Hydrochloride, Acebutolol Hydrochloride Imp. J (EP), Acebutolol Hydrochloride Impurity J as Hydrochloride, Acebutolol Impurity J as Hydrochloride
• CAS: 57898-79-0

Beschreibung

Impurity Acebutolol EP Impurity J
Applications (±)-N-[3-Acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]propanamide Monohydrochloride is an impurity of Acebutolol (A123800), a cardioselective β-adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II). (Acebutolol EP Impurity J)
References Cuthbert, O.A., et al.: Br. J. Pharmacol., 43, 639 (1971), Singh, B.N., et al.: Drugs, 29, 531 (1985), Foster, R.T., et al.: Anal. Profiles Drug Subs., 19, 1 (1990),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 358.86
• Formel: C₁₇H₂₆N₂O₄HCl)
• Farbe/Form: Neat
• InChl: 1H, InChI=1S/C17H26N2O4.ClH/c1-5-17(22)19-13-6-7-16(15(8-13)12(4)20)23-10-14(21)9-18-11(2)3, /h6-8,11,14,18,21H,5,9-10H2,1-4H3,(H,19,22)
• InChI Key: InChIKey=QGRNEYQABUHJRT-UHFFFAOYSA-N
• SMILES: CCC(=O)Nc1ccc(OCC(O)CNC(C)C)c(C(C)=O)c1.Cl