N-Acetyl-L-(-)-leucine

CAS: 1188-21-2

Ref. TR-A185035

Produktinformation

• Name: N-Acetyl-L-(-)-leucine
• Synonyme: L-Leucine, N-acetyl-, Leucine, N-acetyl-, L- (8CI), (S)-2-Acetamido-4-methylpentanoic acid, Acetyl-L-leucine, Acetylleucine, N-Acetylleucine, NSC 206316, (-)-N-Acetyl-<span class="text-smallcaps">L</span>-leucine, (2S)-2-(acetylamino)-4-methylpentanoate, (2S)-2-Acetamido-4-methylpentanoic acid, <span class="text-smallcaps">L</span>-Leucine, N-acetyl-, Ac-Leu-OH, Acetyl-<span class="text-smallcaps">L</span>-leucine, Leucine, N-acetyl-, <span class="text-smallcaps">L</span>-, N-acetylleucine

Beschreibung

Applications N-Acetyl-L-(-)-leucine is used in the preparation of small molecule inhibitors of anti-apoptotic Bcl-2 family proteins. Also used in the preparation of amphiphilic copolymers involving hydrophobic amino acid and oligopeptide side chains for optical tumor imaging in vivo.
References Zheng, C. et al.: Bioorg. Med. Chem. Lett., 22, 39 (2012); Miki, K. et al.: Bull. Chem. Soc. Jap., 85, 1277 (2012);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 173.21
• Formel: C₈H₁₅NO₃
• Farbe/Form: Neat
• InChl: InChI=1S/C8H15NO3/c1-5(2)4-7(8(11)12)9-6(3)10/h5,7H,4H2,1-3H3,(H,9,10)(H,11,12)/t7-/m0/s1
• InChI Key: InChIKey=WXNXCEHXYPACJF-ZETCQYMHSA-N
• SMILES: CC(=O)N[C@@H](CC(C)C)C(=O)O