N-Acetyl D-Alpha-Methyl DOPA Dimethyl Ether

CAS: 2503-39-1

Ref. TR-A186665

Produktinformation

• Name: N-Acetyl D-Alpha-Methyl DOPA Dimethyl Ether
• Synonyme: N-Acetyl-3-methoxy-O,alpha-dimethyl-D-tyrosine, N-Acetyl-3-(3,4-dimethoxyphenyl)-2-methyl-alanine

Beschreibung

Applications N-Acetyl D-α-Methyl DOPA Dimethyl Ether is an intermediate used in the synthesis of R-(+)-Carbidopa (C175986), which is an inhibitor of DOPA decarboxylase, which plays a significant role in the prevention of the conversion of L-DOPA (D533751) to dopamine (D533780). Studies has also indicated the inhibitory effects of towards L-DOPA in human liver prepns and as well as 5-hydroxytryptophan (H975700).
References Vogel, W.H. et al.: Arch. Int. Pharmacodyn. Ther. 198, 85 (1972);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 281.3
• Formel: C₁₄H₁₉NO₅
• Farbe/Form: Neat
• InChl: InChI=1S/C14H19NO5/c1-9(16)15-14(2,13(17)18)8-10-5-6-11(19-3)12(7-10)20-4/h5-7H,8H2,1-4H3,(H,15,16)(H,17,18)/t14-/m1/s1
• InChI Key: InChIKey=VIQGMKBBYLJABC-CQSZACIVSA-N
• SMILES: COc1ccc(C[C@@](C)(NC(C)=O)C(=O)O)cc1OC