Adapalene

CAS: 106685-40-9

Ref. TR-A225000

Produktinformation

• Name: Adapalene
• Synonyme: 6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)naphthalene-2-carboxylic acid, 2-Naphthalenecarboxylic acid, 6-(4-methoxy-3-tricyclo[3.3.1.1^3,7]dec-1-ylphenyl)-, 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid, 6-(4-Methoxy-3-tricyclo[3.3.1.1^3,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid, 6-[3-(1-Adamantyl)-4-Methoxyphenyl]-2-Naphthalene Carboxylic Acid, 6-[3-(1-Adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid, 6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthalenecarboxylic acid, 6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthoic acid, 6-[4-Methoxy-3-(Tricyclo[3.3.1.1~3,7~]Dec-1-Yl)Phenyl]Naphthalene-2-Carboxylic Acid, Aclene, Aclene Gel, Adapalen, CD 271 (pharmaceutical), Cd-271, Differin, Differin Gel, 6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid, 2-Naphthalenecarboxylic acid, 6-(4-methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-

Beschreibung

Applications Retinoid selective for retinoic acid receptor (RAR) subtypes β and γ. Antiacne.
References Griffiths, C.E.M., et al.: J. Invest. Dermatol., 101, 325 (1993), Bernard, B.A., et al.: Skin Pharmacol., 6, 61 (1993), Waugh, J., et al.: Drugs, 64, 1465 (2004),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 412.52
• Formel: C₂₈H₂₈O₃
• Farbe/Form: White
• InChl: InChI=1S/C28H28O3/c1-31-26-7-6-23(21-2-3-22-12-24(27(29)30)5-4-20(22)11-21)13-25(26)28-14-17-8-18(15-28)10-19(9-17)16-28/h2-7,11-13,17-19H,8-10,14-16H2,1H3,(H,29,30)
• InChI Key: InChIKey=LZCDAPDGXCYOEH-UGQIIZBGSA-N
• SMILES: COc1ccc(-c2ccc3cc(C(=O)O)ccc3c2)cc1C12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3