Agomelatine-d4

CAS: 1079389-44-8

Ref. TR-A430002

Produktinformation

• Name: Agomelatine-d4
• Synonyme: N-[2-(7-Methoxy-1-naphthalenyl)ethyl-d4]acetamide, N-[2-(7-Methoxy-1-naphthyl) ethyl]acetamide-d4, S 20098-d4, Valdoxan-d4
• Marke: TRC
• Beschreibung: Applications Labelled Agomelatine, a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Yous, S., et al.: J. Med. Chem., 35, 1484 (1992), Zhdanova, I., et al.: J. Clin. Endocrinol. Metab., 86, 4727 (2001), Cajochen, C., et al.: J. Pineal Res., 35, 149 (2003),

Chemische Eigenschaften

• Molekulargewicht: 247.326
• Formel: C₁₅D₄H₁₃NO₂
• Farbe/Form: Neat
• InChl: InChI=1S/C15H17NO2/c1-11(17)16-9-8-13-5-3-4-12-6-7-14(18-2)10-15(12)13/h3-7,10H,8-9H2,1-2H3,(H,16,17)/i8D2,9D2
• InChI Key: InChIKey=YJYPHIXNFHFHND-LZMSFWOYSA-N
• SMILES: [2H]C([2H])(NC(C)=O)C([2H])([2H])c1cccc2ccc(OC)cc12