Almotriptan Malate N-Oxide

CAS: 1189348-94-4

Ref. TR-A440020

Produktinformation

• Name: Almotriptan Malate N-Oxide
• Synonyme: N,N-dimethyl-2-(5-((pyrrolidin-1-ylsulfonyl)methyl)-1H-indol-3-yl)ethanamine Oxide,Almotriptan Malate Impurity D
• Marke: TRC
• Beschreibung: Applications Almotriptan Malate N-Oxide is a metabolite of Almotriptan (A575200), which is a serotonin 5HT1B /1D-receptor agonist used for treatment of migraine.References Fleishaker, J.C., et al.: Clin. Pharmacol. Ther., 67, 498 (2000), Kamali, F., et al.: Curr. Opin. Cent. Peripher. Nerv. Syst. Invest. Drugs, 2, 197 (2000), Dodick, D.W., et al.: Expert Opin.Pharmacother., 4, 1157 (2003)

Chemische Eigenschaften

• Molekulargewicht: 351.46 + 134.09
• Formel: C₁₇H₂₅N₃O₃S•C₄H₆O₅
• Farbe/Form: Neat
• InChl: InChI=1S/C17H25N3O3S.C4H6O5/c1-20(2,21)10-7-15-12-18-17-6-5-14(11-16(15)17)13-24(22,23)19-8-3-4-9-19;5-2(4(8)9)1-3(6)7/h5-6,11-12,18H,3-4,7-10,13H2,1-2H3;2,5H,1H2,(H,6,7)(H,8,9)
• SMILES: C[N+](C)([O-])CCc1c[nH]c2ccc(CS(=O)(=O)N3CCCC3)cc12.O=C(O)CC(O)C(=O)O