Alclometasone 17,21-Dipropionate

CAS: 66734-13-2

Ref. TR-A514580

Produktinformation

• Name: Alclometasone 17,21-Dipropionate
• Synonyme: (7α,11β,16α)-7-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione, Aclovate, Alclometasone dipropionate, Almeta, Delonal, Sch 22219, Vaderm
• Marke: TRC

Beschreibung

Applications Alclometasone-17,21-dipropionate is an synthetic glucocorticoid steroid used for inflammatory skin conditions. Alclometasone-17,21-dipropionate is topically used in dermatology as an anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent.
References Teraki, Y., et al.: Dermatol., 224, 309 (2012); Yamamoto, Y., et al.: int. J. Pharma., 426. 54 (2012); Aggerwal, A., et al.: J. Int. Med. Res., 10, 414 (1982);

Chemische Eigenschaften

• Molekulargewicht: 521.04
• Formel: C₂₈H₃₇ClO₇
• Farbe/Form: Neat
• InChl: InChI=1S/C28H37ClO7/c1-6-22(33)35-14-21(32)28(36-23(34)7-2)15(3)10-18-24-19(29)12-16-11-17(30)8-9-26(16,4)25(24)20(31)13-27(18,28)5/h8-9,11,15,18-20,24-25,31H,6-7,10,12-14H2,1-5H3/t15-,18+,19-,20+,24-,25+,26+,27+,28+/m1/s1
• InChI Key: InChIKey=DJHCCTTVDRAMEH-DUUJBDRPSA-N
• SMILES: CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@H](C)C[C@H]2[C@H]3[C@H]([C@@H](O)C[C@@]21C)[C@@]1(C)C=CC(=O)C=C1C[C@H]3Cl