Aldosterone

CAS: 52-39-1

Ref. TR-A514700

Produktinformation

• Name: Aldosterone
• Synonyme: Pregn-4-en-18-al, 11,21-dihydroxy-3,20-dioxo-, (11ß)-, Aldosterone (8CI), 11ß,21-Dihydroxy-3,20-diketo-4-pregnen-18-al, 11ß,21-Dihydroxy-3,20-diketopregn-4-ene-18-al, 11ß,21-Dihydroxypregn-4-ene-3,18,20-trione, 18-Formyl-11ß,21-dihydroxy-4-pregnene-3,20-dione, 18-Oxocorticosterone, Aldocorten, Aldocortene, Aldocortin, Electrocortin, Elektrocortin, NSC 73856, Reichstein X, d-Aldosterone, (11β)-11,21-Dihydroxy-3,20-dioxopregn-4-en-18-al, 11β,21-Dihydroxy-3,20-diketo-4-pregnen-18-al, 11β,21-Dihydroxy-3,20-diketopregn-4-ene-18-al, 11β,21-Dihydroxypregn-4-ene-3,18,20-trione, 18-Formyl-11β,21-dihydroxy-4-pregnene-3,20-dione, Aldosteron, Aldosterona, Nsc 73856, Pregn-4-en-18-al, 11,21-dihydroxy-3,20-dioxo-, (11β)-

Beschreibung

Applications Aldosterone is an adrenocortical steroid which exerts regulatory influence on metabolism of electrolytes and water. Biologically active aldosterone isomer; a mineralocorticoid produced by the adrenal cortex that induces urinary excretion of K+ and renal reabsorptioon of Na+. Exists as an equilibrium mixture of the aldehyde and the hemiacetal.
References Simpson, et al.: Experienta, 9, 333 (1953), Morel, A., et al.: Nature, 356, 523 (1992), Arima, S., et al.: Clin. Exp. Nephrol., 7, 172 (2003), Hirasawa, A., et al.: Eur. J. Pharmacol., 267, 71 (1994), Hiroyama, M., et al.: Mol. Endocrinol., 21, 247 (2007),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 360.44
• Formel: C₂₁H₂₈O₅
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1
• InChI Key: InChIKey=PQSUYGKTWSAVDQ-ZVIOFETBSA-N
• SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@]2(C=O)[C@@H](C(=O)CO)CC[C@@H]12