Ambroxol Cyclic Impurity Hydrochloride

CAS: 15942-08-2

Ref. TR-A575910

Produktinformation

• Name: Ambroxol Cyclic Impurity Hydrochloride
• Synonyme: Ambroxol Hydrochloride Imp. B (EP), Ambroxol Imp. B (EP), trans-4-(6,8-Dibromo-1,4-dihydroquinazolin-3(2H)-yl)cyclohexanol Hydrochloride, Ambroxol Hydrochloride Imp. B (EP) as Hydrochloride, trans-4-(6,8-Dibromo-1,4-dihydro-3(2H)-quinazolinyl)cyclohexanol monohydrochloride, Ambroxol Hydrochloride Impurity B as Hydrochloride, Ambroxol Impurity B as Hydrochloride

Beschreibung

Impurity Ambroxol EP Impurity B Hydrochloride
Stability Hygroscopic
Applications Ambroxol Cyclic Impurity is a metabolite as well as an impurity of the bronchosecretolytic drug, Ambroxol (A575900).
References Hammer, R. et al.: Arzneim.-Forsch., 28, 899 (1978); Nieder, M. et al.: HRC & CC, 9, 561 (1986); Huq, F. et al.: J. Pharmacol. Toxicol., 3, 147 (2008);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 426.57
• Formel: C₁₄H₁₈Br₂N₂O·ClH
• Farbe/Form: White To Off-White
• InChl: 1H/t11-,12-, /h5-6,11-12,17,19H,1-4,7-8H2, InChI=1S/C14H18Br2N2O.ClH/c15-10-5-9-7-18(8-17-14(9)13(16)6-10)11-1-3-12(19)4-2-11
• InChI Key: InChIKey=ICLHRFYBPXBCPE-UHFFFAOYSA-N
• SMILES: Cl.OC1CCC(N2CNc3c(Br)cc(Br)cc3C2)CC1