3-Aminodihydro-​d2-2(3H)​-​thiophenone-​4,​5-​d2

CAS: 619320-40-0

Ref. TR-A591301

Produktinformation

• Name: 3-Aminodihydro-​d2-2(3H)​-​thiophenone-​4,​5-​d2
• Synonyme: 3-amino-4,4,5,5-tetradeuteriothiolan-2-one

Beschreibung

Applications 3-Aminodihydro-​d2-2(3H)​-​thiophenone-​4,​5-​d2 is an intermediate in the synthesis of Erdosteine-d4 (E596052), which is the isotope labelled analog of Erdosteine (E596050); a mucolytic developed for the treatment of chronic obstructive bronchitis.
References Kuvandik, G., et al.: Toxicol. Pathol., 36, 714 (2008); Koyu, A., et al.: Mol. Cell. Biochem., 331, 43 (2009); Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2010)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 121.194
• Formel: C₄D₄H₃NOS
• Farbe/Form: Neat
• InChl: InChI=1S/C4H7NOS/c5-3-1-2-7-4(3)6/h3H,1-2,5H2/i1D2,2D2
• InChI Key: InChIKey=KIWQWJKWBHZMDT-LNLMKGTHSA-N
• SMILES: [2H]C1([2H])SC(=O)C(N)C1([2H])[2H]