3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

CAS: 1224844-38-5

Ref. TR-A602050

Produktinformation

• Name: 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
• Synonyme: INK 128, MLN 0128, Sapanisertib
• CAS: 1224844-38-5

Beschreibung

Stability Hygroscopic
Applications 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a potent and selective TORC1/2 inhibitor with broad oral antitumor activity. TORC1/2 inhibitors are mechanistically distinct from rapamycinand offer a compelling approach to the treatment of cancer by targeting translational control, cell metabolism, growth andangiogenesis.
References Katayoun, J., et al.: Molec. Cancer. Therap., 8, 1158 (2009);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 309.33
• Formel: C₁₅H₁₅N₇O
• Farbe/Form: Neat
• InChl: InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
• InChI Key: InChIKey=GYLDXIAOMVERTK-UHFFFAOYSA-N
• SMILES: CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc21