2-Amino-4'-bromoacetophenone Hydrochloride

CAS: 5467-72-1

Ref. TR-A602065

Produktinformation

• Name: 2-Amino-4'-bromoacetophenone Hydrochloride
• Synonyme: 2-Amino-1-(4-bromophenyl)ethan-1-one Hydrochloride, 2-Amino-1-(4-bromophenyl)ethanone Hydrochloride, N-p-Bromophenacylamine Hydrochloride, a-Amino-p-bromoacetophenone Hydrochloride, 2-(4-Bromophenyl)-2-oxoethan-1-aminium chloride, 2-Amino-1-(4-bromophenyl)ethan-1-one hydrochloride, 2-Amino-1-(4-bromophenyl)ethanone hydrochloride, 2-Amino-4'-Bromoacetophenone Hydrochloride, 2-Amino-4'-bromoacetophenone HCl, Acetophenone, 2-amino-4′-bromo-, hydrochloride, Ethanone, 2-amino-1-(4-bromophenyl)-, hydrochloride, Ethanone, 2-amino-1-(4-bromophenyl)-, hydrochloride (1:1), N-p-Bromophenacylamine hydrochloride, α-Amino-p-bromoacetophenone hydrochloride
• CAS: 5467-72-1

Beschreibung

Applications 2-Amino-4'-bromoacetophenone Hydrochloride is used as a reagent in the synthesis of Ledipasvir (L320100); a potent, once-daily oral NS5A inhibitor used for treatment of hepatitis C virus infection. 2-Amino-4'-bromoacetophenone Hydrochloride is also used in the preparation of the β-receptor agonists (-)-Denopamine (D231485) and (-)-Arbutamine (A766300).
References Link, J.O., et al.: J. Med. Chem., 57, 2033 (2014); Shang, G., et al.: Chem-Eur. J., 13, 7780 (2007)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 248.96
• Formel: C₈H₉BrClNO
• Farbe/Form: Neat
• InChl: InChI=1S/C8H8BrNO.ClH/c9-7-3-1-6(2-4-7)8(11)5-10;/h1-4H,5,10H2;1H