3-Amino-5,6-dichloro-2-pyrazinecarboxylic Acid Methyl Ester

CAS: 1458-18-0

Ref. TR-A604770

Produktinformation

• Name: 3-Amino-5,6-dichloro-2-pyrazinecarboxylic Acid Methyl Ester
• Synonyme: 2-Pyrazinecarboxylic acid, 3-amino-5,6-dichloro-, methyl ester, Pyrazinecarboxylic acid, 3-amino-5,6-dichloro-, methyl ester (7CI,8CI,9CI), 3-Amino-5,6-dichloropyrazine-2-carboxylic acid methyl ester, 2-Pyrazinecarboxylic acid, 3-amino-5,6-dichloro-, methyl ester, 3-Amino-5,6-Dichloropyrazine-2-Carboxylic Acid Methyl Ester, Methyl 3-Amino-5,6-Dichloropyrazine-2-Carboxylate, Methyl 3-amino-5,6-dichloro-2-pyrazinecarboxylate, Pyrazinecarboxylic acid, 3-amino-5,6-dichloro-, methyl ester

Beschreibung

Applications 3-Amino-5,6-dichloro-2-pyrazinecarboxylic Acid Methyl Ester, is used for the preparation of 2-Amidino analogs of glycine-Amiloride (A578700) conjugates, acting as inhibitors of the protease urokinase plasminogen activator (uPA), a promising anticancer targets. Dyes and metabolites.
References Massey, A. P., et al.: Bioorg. Med. Chem. Lett., 22, 2635 (2012); Matthews, H., et al.: Bioorg. Med. Chem. Lett., 21, 6760 (2011);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 222.029
• Formel: C₆H₅Cl₂N₃O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C6H5Cl2N3O2/c1-13-6(12)2-5(9)11-4(8)3(7)10-2/h1H3,(H2,9,11)
• InChI Key: InChIKey=USYMCUGEGUFUBI-UHFFFAOYSA-N
• SMILES: COC(=O)c1nc(Cl)c(Cl)nc1N