3’-Amino-2’-Hydroxy-[1,1’]biphenyl-3-carboxylic Acid

CAS: 376592-93-7

Ref. TR-A611255

Produktinformation

• Name: 3’-Amino-2’-Hydroxy-[1,1’]biphenyl-3-carboxylic Acid
• Synonyme: [1,1'-Biphenyl]-3-carboxylic acid, 3'-amino-2'-hydroxy-, 3''-Amino-2''-Hydroxy-Biphenyl-3-Carboxylic Acid, 3'-Amino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid, 3'-Amino-2'-hydroxybiphenyl-3-carboxylic acid

Beschreibung

Applications 3’-Amino-2’-Hydroxy-[1,1’]Biphenyl-3-carboxylic Acid is used in the synthesis of monoethanolamine salts. A hydrazine cleavage product from Eltrombopag (E508000), an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia
References Bussel, J., et al.: New Eng. J. Med., 357, 2237 (2007), Marsilje, T., et al.: Bioorg. Med. Chem. Lett., 18, 5259 (2008), Alper, P., et al.: Bioorg. Med. Chem. Lett., 18, 5255 (2008),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 229.231
• Formel: C₁₃H₁₁NO₃
• Farbe/Form: Neat
• InChl: InChI=1S/C13H11NO3/c14-11-6-2-5-10(12(11)15)8-3-1-4-9(7-8)13(16)17/h1-7,15H,14H2,(H,16,17)
• InChI Key: InChIKey=ZXLYSSHNDUXXIN-UHFFFAOYSA-N
• SMILES: Nc1cccc(-c2cccc(C(=O)O)c2)c1O