3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide

CAS: 76824-16-3

Ref. TR-A611525

Produktinformation

• Name: 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide
• Synonyme: Famotidine Imp. F (EP), Famotidine USP Related Compound F, Famotidine USP RC F, Propanamide, 3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]- (9CI), 3-[[[2-[(Diaminomethylene)-amino]thiazol-4-yl]methyl]sulfanyl]-propanamide, Famotidine Imp. D (EP), Famotidine Related Compound D, Famotidine Impurity D

Beschreibung

Impurity Famotidine EP Impurity D
Stability Hygroscopic
Applications 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide is an impurity in the synthesis of Famotidine (F102250) histamine H2-receptor antagonist. Antiulcerative.
References Takeda, M., et al.: Arzneim.-Forsch., 32, 734 (1982), Miwa, M., et al.: J. Clin. Pharmacol. Ther. Toxicol., 22, 214 (1984), Takabatke, T., et al.: Eur. J. Clin. Pharmacol., 28, 327 (1985),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 259.35
• Formel: C₈H₁₃N₅OS₂
• Farbe/Form: White To Light Yellow
• InChl: InChI=1S/C8H13N5OS2/c9-6(14)1-2-15-3-5-4-16-8(12-5)13-7(10)11/h4H,1-3H2,(H2,9,14)(H4,10,11,12,13)
• InChI Key: InChIKey=BLXXXPVCYVHTQA-UHFFFAOYSA-N
• SMILES: N=C(N)Nc1nc(CSCCC(N)=O)cs1