5-Aminoimidazole-4-carboxamide-1-Beta-D-ribofuranoside

CAS: 2627-69-2

Ref. TR-A611700

Produktinformation

• Name: 5-Aminoimidazole-4-carboxamide-1-Beta-D-ribofuranoside
• Synonyme: 5-Amino-1-ribosyl-4-imidazolecarboxamide, 5-Amino-4-imidazolecarboxamide ribofuranoside, AIC-Riboside, AICA-Riboside, AICAR, Acadesine, Arasine, GP 1-110, NSC 105823,1-Ribosyl-4-carboxamido-5-aminoimidazole
• Marke: TRC

Beschreibung

Applications AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)

Chemische Eigenschaften

• Molekulargewicht: 258.23
• Formel: C₉H₁₄N₄O₅
• Farbe/Form: Neat
• InChl: InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1
• InChI Key: InChIKey=RTRQQBHATOEIAF-UUOKFMHZSA-N
• SMILES: NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1N