5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside-15N4

CAS: 2627-69-2

Ref. TR-A611703

Produktinformation

• Name: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside-15N4
• Synonyme: AICAR-15N4, Acadesine-15N4, 5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide-15N4, 5-Amino-4-imidazole carboxamide Riboside-15N4, Arasine-15N4, GP 1-110-15N4, NSC 105823-15N4
• Marke: TRC
• Beschreibung: Applications A labelled nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)

Chemische Eigenschaften

• Molekulargewicht: 262.20
• Formel: C₉H₁₄₁₅N₄O₅
• Farbe/Form: Neat
• InChl: InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1/i10+1,11+1,12+1,13+1
• InChI Key: InChIKey=RTRQQBHATOEIAF-KUJNSDEASA-N
• SMILES: [15NH2]C(=O)c1[15n]c[15n]([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1[15NH2]