5-Aminoimidazole-4-carboxamide-1-β-D-Ribofuranosyl 5’-Monophosphate Disodium Salt

CAS: 6884-89-5

Ref. TR-A612585

Produktinformation

• Name: 5-Aminoimidazole-4-carboxamide-1-β-D-Ribofuranosyl 5’-Monophosphate Disodium Salt
• Synonyme: 5(4)-Amino-4(5)-imidazolecarboxamide Riboside 5'-Phosphoric Acid Disodium Salt, Sodium ((2R,3S,4R,5R)-5-(5-Amino-4-carbamoyl-1H-imidazol-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl Phosphate
• Marke: TRC
• Beschreibung: Applications 5-Aminoimidazole-4-carboxamide-1-β-D-Ribofuranosyl 5’-Monophosphate Disodium Salt is disodium salt form of 5-Aminoimidazole-4-carboxamide-1-β-D-Ribofuranosyl 5’-Monophosphate (A611705), which causes accumulation of monophosphorylated derivative 5-aminoimidaz ole-4-carboxamide ribonucleoside (ZMP) and consequent phosphorylation and activation of AMP-activated protein kinase (AMPK).References Corton, J., et al.: Eur. J. Biochem., 229, 558 (1995); Towler, M., Hardie, D.: Circ. Res., 100, 328 (2007); Narkar, V., et al.: Cell, 134, 405 (2008)

Chemische Eigenschaften

• Molekulargewicht: 382.175
• Formel: C₉H₁₃N₄Na₂O₈P
• Farbe/Form: Neat
• InChl: InChI=1S/C9H15N4O8P.2Na/c10-7-4(8(11)16)12-2-13(7)9-6(15)5(14)3(21-9)1-20-22(17,18)19;;/h2-3,5-6,9,14-15H,1,10H2,(H2,11,16)(H2,17,18,19);;/q;2*+1/p-2/t3-,5-,6-,9-;;/m1../s1
• InChI Key: InChIKey=VJJWHCXSMLYRNL-LGVAUZIVSA-L
• SMILES: NC(=O)c1ncn([C@@H]2O[C@H](COP(=O)(O[Na])O[Na])[C@@H](O)[C@H]2O)c1N