1-Amino-3-nitroadamantane

CAS: 243145-00-8

Ref. TR-A618130

Produktinformation

• Name: 1-Amino-3-nitroadamantane
• Synonyme: 3-Nitrotricyclo[3.3.1.13,7]decan-1-amine

Beschreibung

Impurity Vildagliptin Impurity
Applications 1-Amino-3-nitroadamantane has potential application in co-catalyst for transition metal reactions and maybe a useful intermediate for the synthesis of Vildagliptin (V305000), an antidiabetic drug that inhibits dipeptidyl peptidase 4 (DPP-4). Vildagliptin exhibits antioxidant properties and may be an apoptotic compound against pancreatic cancer cells.
References Amritha, C., et al.: JCDR 9, FC14 (2015); Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 196.25
• Formel: C₁₀H₁₆N₂O₂
• Farbe/Form: Neat
• SMILES: N[C@@]12C[C@@H]3C[C@@H](C[C@@]([N+](=O)[O-])(C3)C1)C2