O-2-Amino-2-methylpropyl Bilastine-d6

Ref. TR-A621812

Produktinformation

• Name: O-2-Amino-2-methylpropyl Bilastine-d6
• Synonyme: 2-Amino-2-methylpropyl 2-(4-(2-(4-(1-(2-Ethoxymethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)-2-methylpropanoate

Beschreibung

Applications O-2-Amino-2-methylpropyl Bilastine-d6 is an intermediate used in the synthesis of Bilastine-d6 (B385002), which is labelled Bilastine. It is a novel, nonsedating H1-antihistamine developed for symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria.
References Van Cauwenberge, P., et al.: Clin. Exp. Allergy, 30, 891 (2000), Bauchau, V., et al.: Eur. Respir. J., 24, 758 (2004), Lehman, J., et al.: Drugs, 66, 2309 (2006),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 540.77
• Formel: C₃₂D₆H₄₀N₄O₃
• Farbe/Form: Neat
• InChl: InChI=1S/C32H46N4O3/c1-6-38-22-21-36-28-10-8-7-9-27(28)34-29(36)25-16-19-35(20-17-25)18-15-24-11-13-26(14-12-24)32(4,5)30(37)39-23-31(2,3)33/h7-14,25H,6,15-23,33H2,1-5H3/i4D3,5D3
• InChI Key: InChIKey=GFRPXKNUCDOBST-RKAHMFOGSA-N
• SMILES: [2H]C([2H])([2H])C(C(=O)OCC(C)(C)N)(c1ccc(CCN2CCC(c3nc4ccccc4n3CCOCC)CC2)cc1)C([2H])([2H])[2H]