4-(4-Aminophenyl)butyric Acid

CAS: 15118-60-2

Ref. TR-A622565

Produktinformation

• Name: 4-(4-Aminophenyl)butyric Acid
• Synonyme: 4-(p-Aminophenyl)butyric Acid, 4-Aminobenzenebutanoic Acid, NSC 27531, p-Aminophenylbutyric acid, 4-(4-Aminophenyl)Butanoic Acid

Beschreibung

Applications 4-(4-Aminophenyl)butyric Acid is a degradation product of Chlorambucil (C325050); an alkylating agent that is used as an chemotherapy drug in the treatment of chronic lymphocytic leukemia. Chlorambucil is also used to treat non-Hodgkin's lymphoma (NHL) and Hodgkin's disease.
References Chang, S.Y., et al.: J. Pharm. Sci., 69, 80 (1980); Cogia, A., et al.: Leuk. Lymph., 53, 1961 (2012); Tonino, S.H., et al.: Leuk. Lymph., 53, 1785 (2012); Smolej, L., et al.: Curr. Pharma. Design., 18, 3399 (2012)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 179.22
• Formel: C₁₀H₁₃NO₂
• Farbe/Form: Neat
• InChl: InChI=1S/C10H13NO2/c11-9-6-4-8(5-7-9)2-1-3-10(12)13/h4-7H,1-3,11H2,(H,12,13)
• InChI Key: InChIKey=RBHLFWNKEWLHBP-UHFFFAOYSA-N
• SMILES: Nc1ccc(CCCC(=O)O)cc1