6-(4-Aminophenyl)-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid Methyl Ester

CAS: 1466571-07-2

Ref. TR-A626845

Produktinformation

• Name: 6-(4-Aminophenyl)-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid Methyl Ester
• Synonyme: Apixaban Impurity 5

Beschreibung

Applications 6-(4-Aminophenyl)-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid Methyl Ester is an impurity of Apixaban (A726700); a potent, direct, selective, and orally active inhibitor of coagulation factor Xa.
References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); Barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 392.41
• Formel: C₂₁H₂₀N₄O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C21H20N4O4/c1-28-16-9-7-15(8-10-16)25-19-17(18(23-25)21(27)29-2)11-12-24(20(19)26)14-5-3-13(22)4-6-14/h3-10H,11-12,22H2,1-2H3
• InChI Key: InChIKey=AFNRGILKTSJQOP-UHFFFAOYSA-N
• SMILES: COC(=O)c1nn(-c2ccc(OC)cc2)c2c1CCN(c1ccc(N)cc1)C2=O