Produktinformation
- L-Glutamic acid
- N-[4-[[(2,4-diamino-6-pteridinyl)methyl]amino]benzoyl]-
- Glutamic acid
- N-[p-[[(2,4-diamino-6-pteridinyl)methyl]amino]benzoyl]-
- L- (8CI)
- N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
- 4-Aminofolic acid
- 4-Aminopteroylglutamic acid
- APGA
- Aminopterine
- Mehr Synonyme anzeigen
- NSC 739
- Pteramina
- (S)-2-{4-[(2,4-Diaminopteridin-6-yl)methylamino]benzamido}pentanedioic acid
- Methotrexate Imp. B (EP)
- (2S)-2-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]amino]benzoyl]amino]pentanedioic Acid
- Methotrexate Related Compound B
- Methotrexate Impurity B
- (2S)-2-[[4-[(2,4-Diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
- 4-Amino-4-Deoxypteroylglutamate
- 4-Amino-Folicaci
- 4-Amino-Pga[Qr]
- 4-Aminofolic Acid
- 4-Aminofolicacid[Qr]
- 4-Aminopteroylglutamicacid[Qr]
- 4-Diamino-6-Pteridinyl)Methyl)Amino)Benzoyl)-N-(P-(((L-Glutamicaci
- <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]amino]benzoyl]-
- Acide N-[4-[[(2,4-diamino-6-pteridinyl)methyl]amino]benzoyl]-L-glutamique
- Agpa
- Ai3-26079[Qr]
- Apga
- Glutamic acid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl]amino]benzoyl]-, <span class="text-smallcaps">L</span>-
- Glutamic acid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl]amino]benzoyl]-, L-
- L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]amino]benzoyl]-
- N-(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
- N-(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}benzoyl)glutamic acid
- N-[(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}phenyl)carbonyl]-D-glutamic acid
- N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid
- N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]benzoyl]-L-glutaminsaure
- N-[4-[[(2,4-diamino-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
- Nsc 739
- Pteridin-2-Amine
- acido N-[4-[[(2,4-diamino-6-pteridinil)metil]amino]benzoil]-L-glutamico
Impurity Methotrexate EP Impurity B
Applications Aminopterin (Methotrexate EP Impurity B) is a folic acid antagonist. Its actively transported into cells by thefolate transporter. In the cell, its converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, that, in turn, binds to dihydrofolate reductase and inhibits its activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Matherly, L.H., et al.: Cancer Res., 45, 1073 (1985), Rumberger, B.G., et al.: Cancer Res., 50, 4639 (1990), Roy, K., et al.: J. Biol. Chem., 273, 2526 (1998),
Chemische Eigenschaften
Technische Anfrage zu: TR-A628850 Aminopterin
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