5-Aminopyrazine-2-boronic Acid Pinacol Ester

CAS: 947249-41-4

Ref. TR-A629138

Produktinformation

• Name: 5-Aminopyrazine-2-boronic Acid Pinacol Ester
• Synonyme: 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyrazinamine (ACI), (5-Aminopyrazin-2-yl)boronic acid pinacol ester, 2-(5-Aminopyrazin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazin-2-amine
• Marke: TRC
• Beschreibung: Applications 5-Aminopyrazine-2-boronic acid pinacol ester is a reagent for the synthesis of amino-pyrido-indol-carboxamides that acts as a JAK2 inhibitor used in the treatment of myeloproliferative disorder.References Lim, J., et al.: J. Med. Chem., 54, 7334 (2011)

Chemische Eigenschaften

• Molekulargewicht: 526.716
• Formel: C₁₀H₁₆BN₃O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C10H16BN3O2/c1-9(2)10(3,4)16-11(15-9)7-5-13-6-8(12)14-7/h5-6H,1-4H3,(H2,12,14)
• InChI Key: InChIKey=IYPNVUSIMGAJFC-IYNWLQKKSA-M
• SMILES: [2H]C1([2H])C[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@@H]4[C@H](C)CCC(=O)NCCS(=O)(=O)O[Na])[C@@H]3[C@H](O)C[C@@H]2C([2H])([2H])[C@]1([2H])O