9-Amino-1,2,3,4-tetrahydroacridin-1-ol Maleate

CAS: 118909-22-1

Ref. TR-A629900

Produktinformation

• Name: 9-Amino-1,2,3,4-tetrahydroacridin-1-ol Maleate
• Synonyme: 9-amino-1,2,3,4-tetrahydroacridin-1-ol;(Z)-but-2-enedioic acid, (+-)-9-Amino-1,2,3,4-tetrahydro-1-acridinol maleate (1:1) (salt), 1-Acridinol, 9-amino-1,2,3,4-tetrahydro-, (+-)-, (Z)-2-butenedioate (1:1) (salt), 1-Acridinol, 9-amino-1,2,3,4-tetrahydro-, (2Z)-2-butenedioate (1:1), 1-Acridinol, 9-amino-1,2,3,4-tetrahydro-, (2Z)-2-butenedioate (1:1) (salt), Hp 029, Mentane, P 83-6029A, Unii-Yy1Jw04Jcb, Velnacrine hydrogen maleate, Velnacrine maleate

Beschreibung

Applications A potential Alzheimer's Disease therapeutic of low toxicity. Exhibits biochemical and pharmacological profile similar to THA except that it is far less toxic and without measurable liver toxicity in humans.
References Alon, R., et al.: J. Cell Biol., 128, 1243 (1995), Min, W., et al.: J .Immunol., 159, 3508 (1997), Lum, A., et al.: J. Biol. Chem., 277, 20660 (2002), Carvalho, F., et al.: J. Appl. Toxicol., 24, 419 (2004),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 330.34
• Formel: C₁₃H₁₄N₂O·C₄H₄O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C13H14N2O.C4H4O4/c14-13-8-4-1-2-5-9(8)15-10-6-3-7-11(16)12(10)13;5-3(6)1-2-4(7)8/h1-2,4-5,11,16H,3,6-7H2,(H2,14,15);1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChI Key: InChIKey=NEEKVKZFYBQFGT-BTJKTKAUSA-N
• SMILES: Nc1c2c(nc3ccccc13)CCCC2O.O=C(O)/C=C\C(=O)O