9-Amino-1,2,3,4-tetrahydroacridin-1-ol-d3 Maleate

CAS: 1219806-48-0

Ref. TR-A629902

Produktinformation

• Name: 9-Amino-1,2,3,4-tetrahydroacridin-1-ol-d3 Maleate
• Synonyme: 9-Amino-1,2,3,4-tetrahydro-1-acridinol-d3 (2Z)-2-Butenedioate-d3 Maleate, HP 029-d3 Maleate, Mentane-d3 Maleate, P 83-6029A-d3 Maleate, Velnacrine-d3 Hydrogen Maleate, Velnacrine-d3 Maleate, 1-hydroxy tacrine-d3 Maleate

Beschreibung

Applications A potential Alzheimer's Disease therapeutic of low toxicity. Exhibits biochemical and pharmacological profile similar to THA except that it is far less toxic and without measurable liver toxicity in humans.
References Alon, R., et al.: J. Cell Biol., 128, 1243 (1995), Min, W., et al.: J .Immunol., 159, 3508 (1997), Lum, A., et al.: J. Biol. Chem., 277, 20660 (2002), Carvalho, F., et al.: J. Appl. Toxicol., 24, 419 (2004),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 333.35
• Formel: C₁₇H₁₅D₃N₂O₅
• Farbe/Form: Neat
• InChl: InChI=1S/C13H14N2O.C4H4O4/c14-13-8-4-1-2-5-9(8)15-10-6-3-7-11(16)12(10)13;5-3(6)1-2-4(7)8/h1-2,4-5,11,16H,3,6-7H2,(H2,14,15);1-2H,(H,5,6)(H,7,8)/b;2-1-/i7D2,11D
• InChI Key: InChIKey=NEEKVKZFYBQFGT-DPIYXFFGSA-N
• SMILES: O=C(O)/C=C\C(=O)O.[2H]C1([2H])CCc2[nH]c3ccccc3c(=N)c2C1([2H])O