Amprenavir

CAS: 161814-49-9

Ref. TR-A634400

Produktinformation

• Name: Amprenavir
• Synonyme: N-[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-carbamic acid (3S)-tetrahydro-3-furanyl ester, Carbamic acid, [(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3S)-tetrahydro-3-furanyl ester (9CI), Carbamic acid, [3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, tetrahydro-3-furanyl ester, [3S-[3R*(1R*,2S*)]]-, 141W94, APV, Agenerase, Angenerase, KVX 478, Prozei, Samprenavir, VX 478, VX-478, GW 433908G Fosamprenavir Calcium Test Mix 1, GW 773543, GW 569683, GW 638469, GW 638468, GW 569686, GW 783579, GW 833074, GW 634519, GW 587304, GW 461013X, 4949W94 (GW 288003X), GW 395126X, 3489W95, GW 422708X, GW 475728X, GW 327664X, GW 327662X, GW 327663X, 141W94, 141W94, KVX-478, Agenerase, Prozei,, Amprenavir & its intermediates(R&D), Carbamic acid, (1S,2R)-3-(4-aminophenyl)sulfonyl(2-methylpropyl)amino-2-hydroxy-1-(phenylmethyl)propyl-, (3S)-tetrahydro-3-furanyl ester, Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3S)-tetrahydro-3-furanyl ester, Carbamic acid, [3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, tetrahydro-3-furanyl ester, [3S-[3R*(1R*,2S*)]]-, Kvx-478, Vx 478, tetrahydrofuran-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate

Beschreibung

Applications A selective HIV protease inhibitor. An analogue of Ritonavir.
References Adkins, J.C., et al.: Drugs, 55, 837 (1998)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 505.63
• Formel: C₂₅H₃₅N₃O₆S
• Farbe/Form: White To Beige
• InChl: InChI=1S/C25H35N3O6S/c1-18(2)15-28(35(31,32)22-10-8-20(26)9-11-22)16-24(29)23(14-19-6-4-3-5-7-19)27-25(30)34-21-12-13-33-17-21/h3-11,18,21,23-24,29H,12-17,26H2,1-2H3,(H,27,30)/t21-,23-,24+/m0/s1
• InChI Key: InChIKey=YMARZQAQMVYCKC-OEMFJLHTSA-N
• SMILES: CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CCOC1)S(=O)(=O)c1ccc(N)cc1