AR-C133913XX

CAS: 1251765-07-7

Ref. TR-A766550

Produktinformation

• Name: AR-C133913XX
• Synonyme: (1S,2S,3R,5S)-3-[7-Amino-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol, AR-C 133913XX

Beschreibung

Stability Hygroscopic
Applications AR-C133913XX is an metabolte of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).
References Matetzky, S., et al.: Circulation, 109, 3171 (2004); Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007); Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 370.43
• Formel: C₁₄H₂₂N₆O₄S
• Farbe/Form: Neat
• InChl: InChI=1S/C14H22N6O4S/c1-2-5-25-14-16-12(15)9-13(17-14)20(19-18-9)7-6-8(24-4-3-21)11(23)10(7)22/h7-8,10-11,21-23H,2-6H2,1H3,(H2,15,16,17)/t7-,8+,10+,11-/m1/s1
• InChI Key: InChIKey=YTYBSYIHUFBLKV-YKDSUIRESA-N
• SMILES: CCCSc1nc(N)c2nnn([C@@H]3C[C@H](OCCO)[C@@H](O)[C@H]3O)c2n1