Atovaquone

CAS: 95233-18-4

Ref. TR-A793500

Produktinformation

• Name: Atovaquone
• Synonyme: 2-[trans-4-(4-Chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione, 566C80, 1,4-Hydroxynaphthoquinone, 1,4-Naphthalenedione, 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxy-, 1,4-Naphthalenedione,2-, 1,4-Naphthalenedione,2-(4-(4-chlorophenyl)cyclohexyl)-3-hydroxy-, trans, 2-(4-(4'-Chlorophenyl)Cyclohexyl)-3-Hydroxy-1,4-Naphthoquinone, 2-(Trans-4-(4-Chlorophenyl)Cyclohexyl)-3-Hydroxy-1,4-Naphthalenedione, 2-(Trans-4-(4-Chlorophenyl)Cyclohexyl)-3-Hydroxy-1,4-Naphthoquinone, 2-[4-(4-Chlorophenyl)Cyclohexyl]-3-Hydroxynaphthalene-1,4-Dione, 2-[Trans-4-(4-Chlorophenyl)Cyclohexyl]-3-Hydroxynaphthalene-1,4-Dione, 3-[4-(4-Chlorophenyl)Cyclohexyl]-4-Hydroxynaphthalene-1,2-Dione, Acuvel, Bw 556C-80, Bw 566C, Mepron, Mepron (antipneumocystic), Meprone, Samtirel, Wellvone

Beschreibung

Applications Hydroxynaphthoquinone derivative that inhibits mitochondrial electron transport. Antipneumocystic.
References Hudson, A.T., et al.: Drugs Exp. Clin. Res., 17, 427 (1991), Fry, M., et al.: Biochem. Pharmacol., 43, 1545 (1992), El-Sadr, W.M., et al.: N. Engl. J. Med., 339, 1889 (1998),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 366.84
• Formel: C₂₂H₁₉ClO₃
• Farbe/Form: Yellow-Orange
• InChl: InChI=1S/C22H19ClO3/c23-16-11-9-14(10-12-16)13-5-7-15(8-6-13)19-20(24)17-3-1-2-4-18(17)21(25)22(19)26/h1-4,9-13,15,26H,5-8H2/t13-,15-
• InChI Key: InChIKey=KUCQYCKVKVOKAY-CTYIDZIISA-N
• SMILES: O=C1C(O)=C([C@H]2CC[C@H](c3ccc(Cl)cc3)CC2)C(=O)c2ccccc21