3-[(Aminocarbonyl)amino]-5-[4-(4-morpholinylmethyl)phenyl]-2-thiophenecarboxamide

CAS: 494772-86-0

Ref. TR-A794800

Produktinformation

• Name: 3-[(Aminocarbonyl)amino]-5-[4-(4-morpholinylmethyl)phenyl]-2-thiophenecarboxamide
• Synonyme: 3-[(Aminocarbonyl)amino]-5-[4-(morpholin-4-ylmethyl)phenyl]thiophene-2-carboxamide
• Marke: TRC
• Beschreibung: Applications 3-[(Aminocarbonyl)amino]-5-[4-(4-morpholinylmethyl)phenyl]-2-thiophenecarboxamide is a transforming growth factor (TGF)-β-activated kinase 1 (TAK-1) inhibitor. 3-[(Aminocarbonyl)amino]-5-[4-(4-morpholinylmethyl)phenyl]-2-thiophenecarboxamide has potential use in the treatment of certain lymphomas that are particularly susceptible to TAK1 inhibitors such as B cell tumors, solid tumors, or T cell leukemias.

Chemische Eigenschaften

• Molekulargewicht: 360.43
• Formel: C₁₇H₂₀N₄O₃S
• Farbe/Form: Neat
• InChl: InChI=1S/C17H20N4O3S/c18-16(22)15-13(20-17(19)23)9-14(25-15)12-3-1-11(2-4-12)10-21-5-7-24-8-6-21/h1-4,9H,5-8,10H2,(H2,18,22)(H3,19,20,23)
• InChI Key: InChIKey=MOWJKFWTFZWXHW-UHFFFAOYSA-N
• SMILES: NC(=O)Nc1cc(-c2ccc(CN3CCOCC3)cc2)sc1C(N)=O