5-Aza-2'-deoxy Cytidine

CAS: 2353-33-5

Ref. TR-A796950

Produktinformation

• Name: 5-Aza-2'-deoxy Cytidine
• Synonyme: 2'-Deoxy-5-azacytidine, 5-Aza-2-deoxycytidine, 5-Aza-2'-deoxycytidine, 5-Azadeoxycytidine, DAC, Dacogen, Decitabine, NSC 127716,2-Desoxy-5-azacytidine, 4-Amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one, s-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)- (7CI,8CI), beta-Decitabine, 1,3,5-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-, 1,3,5-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-, 2'-Desoxy-5-Azacytidine, 4-Amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin, 4-Amino-1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one, 4-Amino-1-(2-deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-1,3,5-triazin-2(1H)-one, 4-Amino-1-(2-desoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-on, 4-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one, 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one, 4-amino-1-(2-deoxypentofuranosyl)-1,3,5-triazin-2(1H)-one, 4-amino-1-(2-desoxi-β-D-erythro-pentofuranosil)-1,3,5-triazin-2(1H)-ona, 4-amino-1-(2-desoxy-β-D-erythro-pentofurannosyl)-1,3,5-triazine-2(1H)-one, A 2232, Decitabine & its intermediates, Decitabine & its intermediates (R&D), Decitabine intermediates, Nsc 127716, Nsc127716, s-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-, s-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-, β-Decitabine

Beschreibung

Applications 5-Aza-2’-deoxy Cytidine is used as cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines.
References Deng, T., et al.: Life Sci., 84, 311 (2009), Horne, H., et al.: Mol. Cancer Res., 7, 199 (2009), Zinner, R., et al.: Mol. Cancer Ther., 8, 521 (2009),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 228.21
• Formel: C₈H₁₂N₄O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C8H12N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h3-6,13-14H,1-2H2,(H2,9,11,15)/t4-,5+,6+/m0/s1
• InChI Key: InChIKey=XAUDJQYHKZQPEU-JKUQZMGJSA-N
• SMILES: N=c1ncn([C@@H]2C[C@H](O)[C@@H](CO)O2)c(O)n1