2,4-Bis(trimethylsilyl)cytosine

CAS: 18037-10-0

Ref. TR-B101910

Produktinformation

• Name: 2,4-Bis(trimethylsilyl)cytosine
• Synonyme: N-trimethylsilyl-2-trimethylsilyloxypyrimidin-4-amine, 1,1,1-Trimethyl-N-[2-[(trimethylsilyl)oxy]pyrimidin-4-yl]silanamine, 4-Pyrimidinamine, N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]-, Bis(Trimethylsilyl)Cytosine, Bistrimethylsilylcytosine, N-(Trimethylsilyl)-2-[(Trimethylsilyl)Oxy]-4-Pyrimidinamin, N-(Trimethylsilyl)-2-[(trimethylsilyl)oxy]-4-pyrimidinamine, N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]pyrimidin-4-amine, O,N-Bis(trimethylsilyl)cytosine, O2,N4-Bis(trimethylsilyl)cytosine, Pyrimidine, 2-(trimethylsiloxy)-4-[(trimethylsilyl)amino]-
• CAS: 18037-10-0

Beschreibung

Applications 2,4-Bis(trimethylsilyl)cytosine is an intermediate used in the synthesis of 1’-Epi Gemcitabine Hydrochloride (E588510), which is an α-Anomer of Gemcitabine.
References Hertel, L.W., et al.: Cancer Res., 50, 4417 (1990), Abbruzzese, J.L., et al.: J. Clin. Oncol., 9, 491 (1991), Ruiz, V.W.T., et al.: Biochem. Pharmacol., 46, 762 (1993),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 255.464
• Formel: C₁₀H₂₁N₃OSi₂
• Farbe/Form: Neat
• InChl: InChI=1S/C10H21N3OSi2/c1-15(2,3)13-9-7-8-11-10(12-9)14-16(4,5)6/h7-8H,1-6H3,(H,11,12,13)
• InChI Key: InChIKey=IWEHUWMQLZFGLL-UHFFFAOYSA-N
• SMILES: C[Si](C)(C)Nc1ccnc(O[Si](C)(C)C)n1