Baicalein Monohydrate

CAS: 352000-07-8

Ref. TR-B115250

Produktinformation

• Name: Baicalein Monohydrate
• Synonyme: 5,6,7-Trihydroxyflavone Monohydrate, 5,6,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one Hydrate, 4H-1-Benzopyran-4-one, 5,6,7-trihydroxy-2-phenyl-, monohydrate, 4H-1-Benzopyran-4-one, 5,6,7-trihydroxy-2-phenyl-, hydrate (1:1)

Beschreibung

Applications An inhibitor of 12-lipoxygenase, leukotriene biosynthesis and release of lysosomal enzymes. It also inhibits cellular Ca2+ uptake and mobilization and adjuvant-induced arthritis. Baicalein is the flavonoid component of Nepalese and Sino-Japanese crude drugs.
References Nadler, J.L., et al.: J. Clin. Invest., 80, 1763 (1987), Ono, K., et al.: Biochem. Biophys. Res. Commun., 160, 982 (1989), Abe, K., et al.: Chem. Pharm. Bull., 38, 209 (1990)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 288.26
• Formel: C₁₅H₁₂O₆
• Farbe/Form: Neat
• InChl: InChI=1S/C15H10O5.H2O/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12;/h1-7,17-19H;1H2
• InChI Key: InChIKey=NPXBMGZSFXMEQA-UHFFFAOYSA-N
• SMILES: O.O=c1cc(-c2ccccc2)oc2cc(O)c(O)c(O)c12