BAPTA

CAS: 85233-19-8

Ref. TR-B123500

Produktinformation

• Name: BAPTA
• Synonyme: 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic Acid, N,N'-[1,2-Ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)glycine, 1,2-Bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid, 2,2',2'',2'''-[Ethane-1,2-Diylbis(Oxybenzene-2,1-Diylnitrilo)]Tetraacetate, 2,2',2'',2'''-[Ethane-1,2-Diylbis(Oxybenzene-2,1-Diylnitrilo)]Tetraacetic Acid, 2-[2-[2-[2-[Bis(carboxymethyl)amino]phenoxy]ethoxy]-N-(carboxymethyl)anilino]acetic acid, Bapta, Glycine, N,N′-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)-, N,N′-[1,2-Ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)glycine]
• CAS: 85233-19-8

Beschreibung

Applications BAPTA is a highly selective calcium chelating reagent. Lipophilic diesters of the chelating agent 1,2-Bis(2 aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA) are used for inhibition of proteolytic activities of certain metalloproteinases, calpain and TACE.
References Tsien, R.Y., Biochemistry, 19, 2396 (1980), Wu, S.Y., et al.: J. Neurophysiology, 74, 2600 (1995), Venant, A., et al.: Biol. Cell, 85, 197 (1995), Tucker, T., et al.: Neuron, 15, 1323 (1995)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 476.43
• Formel: C₂₂H₂₄N₂O₁₀
• Farbe/Form: Off-White to Light Beige Solid
• InChl: InChI=1S/C22H24N2O10/c25-19(26)11-23(12-20(27)28)15-5-1-3-7-17(15)33-9-10-34-18-8-4-2-6-16(18)24(13-21(29)30)14-22(31)32/h1-8H,9-14H2,(H,25,26)(H,27,28)(H,29,30)(H,31,32)
• InChI Key: InChIKey=FTEDXVNDVHYDQW-UHFFFAOYSA-N
• SMILES: O=C(O)CN(CC(=O)O)c1ccccc1OCCOc1ccccc1N(CC(=O)O)CC(=O)O