Belinostat Ethyl Acetate

CAS: 1137621-29-4

Ref. TR-B131488

Produktinformation

• Name: Belinostat Ethyl Acetate
• Synonyme: (E)-Ethyl 3-(3-(N-Phenylsulfamoyl)phenyl)acrylate

Beschreibung

Applications Belinostat Ethyl Acetate is an intermediate in the synthesis of Belinostat Acid (B131485). Belinostat Acid is a metabolite of Belinostat (B131400), a novel histone deacetylase 3 selective inhibitor, which protects the β cells from cytokine-induced apoptosis.
References Chou, D.H., et al.: Chem. Biol., 19, 669 (2012); Hwang, J.J., et al.: Inves. New. Drugs., 30, 1434 (2012); Dizon, D.S., et al.: Gynecol. Oncol., 125, 367 (2012);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 331.39
• Formel: C₁₇H₁₇NO₄S
• Farbe/Form: Light brown solid
• InChl: InChI=1S/C17H17NO4S/c1-2-22-17(19)12-11-14-7-6-10-16(13-14)23(20,21)18-15-8-4-3-5-9-15/h3-13,18H,2H2,1H3/b12-11+
• InChI Key: InChIKey=IBGWMJSZBGFJCA-VAWYXSNFSA-N
• SMILES: CCOC(=O)/C=C/c1cccc(S(=O)(=O)Nc2ccccc2)c1