6-Destrifluoromethyl-5-trifluoromethyl Bendroflumethiazide (Impurity)

Ref. TR-B133515

Produktinformation

• Name: 6-Destrifluoromethyl-5-trifluoromethyl Bendroflumethiazide (Impurity)
• Synonyme: 3-benzyl-1,1-dioxo-5-(trifluoromethyl)-3,4-dihydro-2H-1?6,2,4-benzothiadiazine-7-sulfonamide
• Marke: TRC
• Beschreibung: Applications 6-Destrifluoromethyl-5-trifluoromethyl Bendoflumethiazide is an impurity of Bendroflumethiazide (B133500), a thiazide diuretic that is used to treat patients with Arterial Hypertensive Disease. Bendroflumethiazide works by blocking sodium reabsorption in the distal tubules within the kidneys.References Borgström, L., et al.: J. Pharmacokinet. Biop., 8,431 (1981); Castillo, A., et al.: FASEB J., 23, 805 (2009); Greible, H., et al.: Arch. Intern. Med., 110, 34 (1962); Hallin, L. & Hansson, L.: J. Cardiovasc. Pharm., 5, 1083 (1983)

Chemische Eigenschaften

• Molekulargewicht: 421.415
• Formel: C₁₅H₁₄F₃N₃O₄S₂
• Farbe/Form: Neat
• InChl: InChI=1S/C15H14F3N3O4S2/c16-15(17,18)11-7-10(26(19,22)23)8-12-14(11)20-13(21-27(12,24)25)6-9-4-2-1-3-5-9/h1-5,7-8,13,20-21H,6H2,(H2,19,22,23)
• InChI Key: InChIKey=URSDPOASTUQARP-UHFFFAOYSA-N
• SMILES: NS(=O)(=O)c1cc(C(F)(F)F)c2c(c1)S(=O)(=O)NC(Cc1ccccc1)N2