Benzarone

CAS: 1477-19-6

Ref. TR-B185150

Produktinformation

• Name: Benzarone
• Synonyme: Benzbromarone Imp. C (EP), (2-Ethyl-3-benzofuranyl)(4-hydroxyphenyl)methanone, (2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone, 2-Ethyl-3-(4-hydroxybenzoyl)benzofuran, 2-Ethyl-3-(p-hydroxybenzoyl)benzofuran, 2-Ethyl-3-benzofuranyl p-hydroxyphenyl ketone, 2-Ethyl-4'-hydroxy-3-benzoylbenzofuran, Benzaron, Fagivil, Fragivil, Fragivix, L 2179-Labaz, L 2197, NSC 82134, Benzbromarone Impurity C, (2-Ethyl-1-Benzofuran-3-Yl)(4-Hydroxyphenyl)Methanone, 2-Ethyl-3-p-hydroxybenzoylbenzofuran, 2-Ethyl-4′-hydroxy-3-benzoylbenzofuran, Ketone, 2-ethyl-3-benzofuranyl p-hydroxyphenyl, Methanone, (2-ethyl-3-benzofuranyl)(4-hydroxyphenyl)-

Beschreibung

Applications Benzarone is an EYA (Eyes Absents), multifunctional protein involved in organogenesis, inhibitor which makes it a potent anticancer agent. EYA’s are over expressed in ovarian and breast cancers. As well it is involved in the synthesis of Human Uric Acid Transporter 1 inhibitors which may be used to treat kidney diseases.
References Tadjuidje, E. et al.: PLoS One., 7, 34806 (2012); M, Wempe, et al.: J. Med. Chem., 54, 2701 (2011);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 266.29
• Formel: C₁₇H₁₄O₃
• Farbe/Form: Neat
• InChl: InChI=1S/C17H14O3/c1-2-14-16(13-5-3-4-6-15(13)20-14)17(19)11-7-9-12(18)10-8-11/h3-10,18H,2H2,1H3
• InChI Key: InChIKey=RFRXIWQYSOIBDI-UHFFFAOYSA-N
• SMILES: CCc1oc2ccccc2c1C(=O)c1ccc(O)cc1