(1R,3S,5R)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid

CAS: 197142-34-0

Ref. TR-B201955

Produktinformation

• Name: (1R,3S,5R)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid
• Synonyme: (1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid 2-tert-butyl Ester, (1R,3S,5R)-2-tert-butoxycarbonyl-2-azabicyclo[3.1.0]hexane-3-carboxylic acid, (1R,3S,5R)-2-aza-bicyclo[3.1.0]hexane-2,3-dicarboxylic acid 2-tert-butyl ester, (4R,5R)-metano-N-Boc-L-proline, N-Boc-L-trans-4,5-methanoproline

Beschreibung

Applications 1R,3S,5R)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid acts as a reagent in the preparation of fused bicycles end-capped with peptide derivatives as HCV inhibitors. Synthesis of (tert-butoxycarbonyl)azabicyclohexanecarboxylic acid via stereoselective cyclopropanation of pyrroline
References Wang, G., et al.: Tetrahedron Lett., 54, 6722 (2013); Belema, M., et al.: From U.S. Pat. Appl. Publ. (2012), US 20120195857 A1 20120802

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 227.26
• Formel: C₁₁H₁₇NO₄
• Farbe/Form: Neat
• InChl: InChI=1S/C11H17NO4/c1-11(2,3)16-10(15)12-7-4-6(7)5-8(12)9(13)14/h6-8H,4-5H2,1-3H3,(H,13,14)/t6-,7-,8+/m1/s1
• InChI Key: InChIKey=VXIIZQXOIDYWBS-PRJMDXOYSA-N
• SMILES: CC(C)(C)OC(=O)N1[C@H](C(=O)O)C[C@H]2C[C@H]21